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GBF Scientific Director: Professor Dr. Rudi Balling

 

Born:              17th October 1953, Germany

 Education:

 1974-1980:     Study of Nutrition at the University of Bonn (B.Sc. 1980) and at Washington State University, Pullman, WA / USA (M.Sc. 1980)

1981-1984 Ph.D. at the Institute of Anatomy and Reproductive Biology, RWTH Aachen

1985-1986             Postdoc at Mount Sinai Research Institute in Toronto / Canada

 Scientific career:

 1987-1991             Scientist at the Max Planck Institute for Biophysical Chemistry, Göttingen

1991-1993             Junior Research Group Leader at the Max Planck Institute for Immunology, Freiburg

1993-2000             Director of the Institute for Mammal Genetics, GSF Neuherberg

2001-               Scientific Director of the GBF, Braunschweig

   Selected publications:

  1. Auwerx, J., Avner, P., Baldock, R., Ballabio, A., Balling, R. et al (2004): The European dimension for the mouse genome mutagenesis program. Nature Genetics 2004, Sept; 36 (9): 925-7
  2. Buer, J., Balling, R. (2003): Mice, microbes and models of infection. Nat. Rev. Genetics 2003 March; 4(3): 195-205
  3. Erben, R.G., Soegiarto, K., Weber, Zeitz, U., Lieberherr, M., Gniadecki, R., Möller, G.,   Adamski, J. & Balling, R. (2002): Deletion of deoxyribonucleic acid binding domain of the vitamin D receptor abrogates genomic and nongenomic functions of vitamin D. Mol. Endocrinol. 16, 1524-1537
  4. Balling, R., (2001): ENU mutagenesis: analyzing gene function in mice. Ann. Rev. Genomics Hum. Genetics 2, 463-492
  5. Hrabé de Angelis, M., Flaswinkel, H., Fuchs, H., Rathkolb, B., Soewarto, D., Marschall,S., Heffner, S., Pargent, W., Wuensch, K., Jung, M., Reis, A., Richter, T.,Alessandrini,    F., Jacob, T., Fuchs, E., Kolb, H., Kremmer, E., Behrend, H., Ring, J., Zimmer, A., Pfeffer, K., Schughart, K., Wolf, E. & Balling, R. (2000): Genome wide large scale production of mutant mice by ENU mutagenesis. Nature Genetics 25, 444-447
  6. Peters, H., Neubüser, A. & Balling, R. (1998): Role of Pax9 in craniofacial and endoderm derived organ development. Gen. & Dev.12, 2735-2747
  7. Neubüser, A., Peters, H., Balling, R. & Martin, G.R. (1997): Antagonistic interactions between FGF and BMP signalling pathways: a  mechanism for positioning the sites of tooth formation. Cell 25, 247-255
  8. Peters, H., Wilm, B., Sakai, H., Imai, K., Maas, R., Balling, R. (1999): Pax1 and Pax9 synergistically regulate vertebral column development. Development. 1999 Dec; 126 (23): 5399-408.
  9. Peters, H., Neubüser, A., Kratochwil, K., Balling, R. (1998): Pax9-deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities. Genes Dev. 1998 Sept. 1; 12 (17): 2735-47.

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